Research Reveals Dog Obesity Gene Shared by Humans
Obesity on the Rise in Dogs and Humans
Obesity is on the rise not just in humans but in dogs, whose history of selective breeding makes them an ideal species for studying the balance between genetics, diet, and lifestyle in weight gain.
Gene Linked to Obesity in Dogs and Humans
A new paper published in the journal Science identified a gene strongly linked to obesity in pet pooches – and found it is also associated with weight gain in humans. The gene, called DENND1B, exerts the most influence on weight gain, according to researchers.
Study Methodology
The team, led by University of Cambridge researcher Eleanor Raffan, collected slobber samples from 241 dogs and conducted a genome-wide association study, examining an organism’s entire set of genes to identify areas linked to a specific trait. They found that the top five genes were also present in humans.
Key Findings
The experts also assessed how much the dogs pestered their owners for food and whether they were fussy eaters. Low-risk dogs tended to remain a healthy weight, regardless of how their owners managed their food and exercise. However, high-genetic-risk dogs were more likely to become overweight, even with regular exercise and healthy eating habits.
Implications for Humans
The study has significant implications for human health, suggesting that genetics play a larger role in weight gain than previously thought. Raffan notes that understanding the biological nuances of obesity can improve treatment and management strategies.
Conclusion
The study highlights the importance of considering individual genetic risk factors in the battle against obesity, whether in dogs or humans. By acknowledging the role of genetics, we can develop more effective strategies for maintaining a healthy weight.
Frequently Asked Questions
Q: What is the significance of the study?
A: The study sheds new light on the role of genetics in weight gain and provides a framework for understanding individual risk factors.
Q: What are the implications for human health?
A: The study suggests that genetics play a larger role in weight gain than previously thought, and that understanding these factors can improve treatment and management strategies.
Q: What is the takeaway for dog owners?
A: The study suggests that even with regular exercise and healthy eating habits, high-genetic-risk dogs may still become overweight. Owners should be aware of their dog’s genetic predisposition and take extra steps to promote a healthy weight.
Q: What are the potential applications of the study?
A: The study has potential applications in the development of anti-obesity drugs and personalized weight management strategies.